PODCAST: Berkeley to Biostats: Greg Enas’s Journey of Leadership and Innovation

July 8, 2025

Welcome back to More Than a Broker.

Greg Enas, an individual whose professional journey is as unique as it is inspiring. His story begins in the tumultuous 1960s in Berkeley, California, a childhood shaped by social upheaval and a working-class neighborhood that fostered resilience. From these formative years, Greg embarked on a career path that took several unexpected, yet profoundly impactful, turns, ultimately leading him to a distinguished 30-year tenure at Eli Lilly and Company.

Throughout our conversation, Greg generously shared invaluable insights into the essence of leadership, the relentless pursuit of innovation, and the fascinating, ever-evolving world of pharmaceuticals. His narrative offers a rare glimpse into the strategic thinking and personal dedication required to navigate complex industries and build a lasting legacy.

About Greg Enas

Greg Enas headshotGreg Enas is currently a Venture Catalyst as the founder of Innovatov LLC, where he assists leaders across both for-profit and not-for-profit sectors in creating better enterprises, communities, and environments, allowing the world to be part of something greater than itself.

Greg attended Biola University in California, where he earned a BS in Mathematical Sciences, and later headed to the opposite coast to attend the Medical College of Virginia at Virginia Commonwealth University, where he earned a Ph.D. in Biostatistics.

From 1982 to 2011, Greg served at Eli Lilly and Company in Indianapolis, Indiana. He started as a senior statistician and was promoted into management in Statistical and Mathematical Sciences, Decision Sciences, and US Regulatory Affairs. He was responsible for external negotiation with governmental regulators and internal leadership for building capabilities and capacity for growth and impact.

Greg is also the co-founder of Citizen 7, a crowdsourcing organization that brings together men of various backgrounds to unite around different initiatives in the city to heal and grow the good in Indianapolis. Greg was also the founding Board Chair of The Oaks Academy from Jan 1998 to December 2006.

10 Reasons to Listen

    • Inspiring Career Journey: Learn how an unexpected turn from an aspiring doctor to biostatistician led to a remarkable 30-year career at a pharmaceutical giant.

    • Inside Look at Eli Lilly’s Evolution: Get a unique perspective on how a major pharmaceutical company transformed from punch cards to pioneering AI in drug development.

    • Navigating Corporate Crises: Hear firsthand how Greg and his team tackled major challenges, including the early controversies surrounding Prozac, and helped save the company.

    • The True Cost of Drug Development: Gain a deeper appreciation for the immense time, effort, and billions of dollars required to bring life-saving drugs to market.

    • Insights into Pharmaceutical Regulation: Understand the complex process of getting drugs approved by health authorities like the FDA and the strategic work involved.

    • Redefining Leadership: Discover Greg’s unconventional, yet highly effective, leadership philosophy, including his unique approach to flipping the organizational chart.

    • Mentorship Matters: Learn about the profound impact key mentors had on Greg’s professional and personal life, from his math professor to his father.

    • Developing Future Leaders: Hear practical advice on how to identify, develop, and empower young talent, even if it means sacrificing short-term gains for long-term success.

    • Beyond the Bottom Line: Explore Greg’s perspective on measuring success in management, emphasizing ethics, humility, and a willingness to sacrifice for the collective good.

    • Having a Career NorthStar: Be inspired by Greg’s dedication to making a difference, from his corporate career focused on human health to his current role as a community builder in Indianapolis.

Greg Enas’s journey is a testament to the power of adaptability, mentorship, and a commitment to ethical, servant leadership in driving both personal and organizational success.